Hepatophrenic ligament

Medically Reviewed by Anatomy Team

The hepatophrenic ligament is a peritoneal fold that connects the liver to the diaphragm, thus forming part of the peritoneal ligaments in the abdominal cavity.

Structure and Anatomy

The hepatophrenic ligament is composed of peritoneal tissue, which is a thin, slippery membrane that lines the abdominal and pelvic cavities and covers most of the abdominal organs. This ligament is part of the larger coronary ligament that also connects the liver to the diaphragm, but the hepatophrenic portion specifically refers to the area extending from the liver to the diaphragm’s right side.

Location

The hepatophrenic ligament is located in the upper right quadrant of the abdominal cavity. It extends from the bare area of the liver to the diaphragm’s underside. The bare area of the liver is the surface that directly contacts the diaphragm and is not covered by peritoneum except at the margins where the hepatophrenic ligament is formed.

Function

The primary function of the hepatophrenic ligament is to help anchor the liver in place within the abdominal cavity, preventing it from moving significantly with changes in body position or with abdominal pressure variations. It helps maintain the position of the liver relative to the diaphragm and the rest of the abdominal organs.

Clinical Significance

The hepatophrenic ligament can be involved in various clinical conditions:

  • Infections and Fluid Collection: Infections or fluid can accumulate in the area between the liver and diaphragm, known as the subphrenic space, which can be subdivided by the hepatophrenic ligament. Abscesses in this area can be difficult to treat and may require surgical drainage.
  • Surgical Reference: During abdominal surgeries, particularly those involving the liver or diaphragm, the hepatophrenic ligament serves as an important anatomical landmark. Its recognition is crucial for proper orientation and for avoiding damage to surrounding structures.
  • Injuries: Trauma to the upper abdomen can result in injuries to the hepatophrenic ligament, which may lead to bleeding or contribute to the displacement of the liver.
  • Diagnostic Imaging: In radiological examinations, such as ultrasound, CT, or MRI, the hepatophrenic ligament can sometimes be visualized and assessed for abnormalities, such as thickening or the presence of abnormal masses.

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