Labia majora

Medically Reviewed by Anatomy Team

The labia majora are the larger, outer folds of skin surrounding the vulva, the external part of the female genitalia. These fleshy structures extend from the mons pubis, the area over the pubic bone, down to just above the perineum. They enclose and protect the more delicate inner parts of the vulva, such as the labia minora, clitoris, and vaginal opening. The labia majora vary in size, shape, and color among individuals, and they often contain hair on the outer surface post-puberty, while the inner surface remains smooth and hairless. Their appearance can also change with age and hormonal factors.

Structure and Anatomy

External Structure

The labia majora are the large, fleshy, outer folds of the vulva. They are longitudinal, running from the mons pubis down to just before the perineum. The outer surface of the labia majora is covered with skin, which after puberty usually has pubic hair. This outer surface also contains sebaceous (oil) glands and sweat glands, which help maintain the skin’s moisture and cleanliness. The color of the labia majora can vary depending on an individual’s skin tone, and the texture is somewhat wrinkled or folded due to the loose connective tissue beneath.

Internal Structure

Beneath the skin, the labia majora contain a significant amount of fatty tissue, which gives them their thickness and softness. This fatty tissue helps provide a cushion and protection for the structures within the vulva. The labia majora also contain smooth muscle fibers, which give them some flexibility and mobility. These muscle fibers are arranged in a loose, irregular pattern.

Blood Supply

The labia majora are richly supplied with blood, mainly from branches of the internal and external pudendal arteries. The external pudendal artery originates from the femoral artery, while the internal pudendal artery arises from the internal iliac artery. This rich vascular network contributes to the warmth and color of the labia majora.

Nerve Supply

The labia majora have a complex nerve supply, which allows them to be sensitive to touch, pressure, and temperature. Sensory innervation comes from the ilioinguinal nerve and the genitofemoral nerve, as well as the pudendal nerve. This rich nerve supply is responsible for the sensitivity and tactile feedback in the area.

Lymphatic Drainage

The lymphatic system of the labia majora is connected to the superficial inguinal lymph nodes. These lymph nodes are located in the groin area and are part of the body’s immune and drainage system, playing a role in filtering out waste and toxins from the region.

Skin and Mucosa Junction

The labia majora have an important junction between the external skin and the inner mucosa. The outer surface is keratinized skin, similar to the skin on other parts of the body. As the folds curve inward, the skin transitions into a mucous membrane, which is thinner, more delicate, and lacks hair follicles. This transition area is typically found along the inner aspect of the labia majora, close to where they meet the labia minora.

Variability

The size, shape, and symmetry of the labia majora vary greatly among individuals. Some labia majora are thicker and more prominent, while others may be thinner and less pronounced. Additionally, the labia majora may become more elongated or lose some of their fatty tissue with age.

Function

Protection

The primary function of the labia majora is to provide protection for the internal structures of the vulva. They act as a physical barrier, shielding the more delicate labia minora, clitoris, vaginal opening, and urethral opening from external trauma, friction, and environmental contaminants. This protective role is crucial in preventing injury or infection of the sensitive inner genital tissues, which are more prone to irritation and damage.

Moisture Control

The labia majora contain sebaceous glands (oil glands) and sweat glands that contribute to maintaining the moisture balance of the vulva. The sebaceous glands secrete oils that keep the skin of the labia majora supple and prevent it from becoming too dry. This moisture control helps maintain the health of the skin and mucosa in the genital area, reducing the risk of cracks or dryness that could lead to irritation or infection.

Thermal Insulation

Due to the fatty tissue present in the labia majora, they serve as a source of thermal insulation for the vulva. This fatty layer helps regulate the temperature of the genital area, protecting the internal reproductive organs from extreme temperatures. It also ensures that the vaginal environment remains at an optimal temperature for reproductive functions.

Support for Vaginal Structure

The labia majora provide structural support to the vaginal opening and surrounding tissues. Their thickness and flexibility help maintain the anatomical integrity of the vulva, offering stability to the vaginal area during movement. This support is particularly important during activities such as walking, running, or sitting, as it helps prevent undue pressure or strain on the inner genital structures.

Sexual Sensation and Arousal

While the labia majora are less sensitive than the labia minora and clitoris, they still play a role in sexual sensation and arousal. The nerve endings within the labia majora can respond to touch, pressure, and temperature changes, contributing to sexual pleasure. During sexual arousal, the labia majora can also become engorged with blood, swelling slightly as a part of the body’s physiological response to stimulation.

Shield Against External Infections

By covering and partially enclosing the inner genital organs, the labia majora act as a protective barrier against pathogens that could enter the vaginal and urethral openings. Their ability to secrete sweat and oil helps in maintaining a hygienic environment by keeping the area clean and less prone to bacterial or fungal growth. This shield function is important in reducing the risk of infections such as urinary tract infections (UTIs) and other vulvovaginal infections.

Role in Reproductive Health

Though not directly involved in reproduction, the labia majora play a supportive role in reproductive health by helping to maintain a balanced environment for the reproductive organs. By protecting the inner genitalia and regulating temperature and moisture levels, they indirectly contribute to conditions that support reproductive health. In this way, they help preserve the health and functionality of the reproductive system.

Clinical Significance

The labia majora play an important role in both general and reproductive health, and changes or abnormalities in this area can have clinical implications. Infections, such as folliculitis or abscesses, may develop due to clogged sebaceous glands or hair follicles, often caused by irritation, poor hygiene, or friction. Infections like vulvovaginitis or sexually transmitted infections (STIs) may also affect the labia majora, given their proximity to the vaginal opening.

The labia majora can also be subject to benign growths like cysts, lipomas, or more rarely, malignancies such as vulvar cancer. Trauma to the area, whether from childbirth or injury, can result in swelling, bruising, or lacerations, which may require medical attention.

Labial hypertrophy, a condition where the labia majora are unusually enlarged, may cause discomfort during activities like walking or sexual intercourse. In such cases, surgical interventions like labiaplasty may be considered for relief.

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