Pterygopalatine fossa

Medically Reviewed by Anatomy Team

The pterygopalatine fossa is a small, complex space located within the head and neck region. It is situated within the posterior aspect of the oral cavity and is bounded by several important structures including the sphenoid bone, the maxilla, and the palatine bone. The pterygopalatine fossa plays a crucial role in the functioning of the head and neck, and its clinical significance lies in the various structures and pathways that pass through it.

Structure and Location

The pterygopalatine fossa is a triangular-shaped space that is located within the posterior aspect of the oral cavity, just behind the maxillary sinus. It is bounded by several bones including the sphenoid bone, the maxilla, and the palatine bone. The pterygopalatine fossa is divided into two main compartments by a thin bony partition known as the pterygoid septum. The anterior compartment is smaller and is separated from the oral cavity by the palatine bone and the posterior pharyngeal wall. The posterior compartment is larger and is separated from the infratemporal fossa by the pterygoid process of the sphenoid bone.

Several important structures and pathways pass through the pterygopalatine fossa, including the maxillary artery, the pterygopalatine ganglion, the pterygoid canal, and the pterygoid venous plexus. The maxillary artery is a branch of the external carotid artery and it enters the pterygopalatine fossa through the pterygomaxillary fissure. The pterygopalatine ganglion is a parasympathetic ganglion located within the pterygopalatine fossa that receives innervation from the maxillary division of the trigeminal nerve (CN V2). The pterygoid canal is a narrow canal that runs through the pterygoid process of the sphenoid bone and contains the pterygoid venous plexus. The pterygoid venous plexus is a network of veins that drain blood from the head and neck region.

Function

The pterygopalatine fossa plays a crucial role in the functioning of the head and neck region. It serves as a passageway for several important structures and pathways, including the maxillary artery, the pterygopalatine ganglion, and the pterygoid canal. The maxillary artery supplies blood to the head and neck region and is essential for maintaining proper circulation. The pterygopalatine ganglion is involved in the regulation of secretions and blood flow in the head and neck region. The pterygoid canal and the pterygoid venous plexus are important for the drainage of blood from the head and neck region.

In addition to its role in the circulation and innervation of the head and neck region, the pterygopalatine fossa also plays a role in the functioning of the maxillary sinus. The maxillary sinus is a large, air-filled cavity located within the maxilla and it serves as a resonating chamber for the voice. The pterygopalatine fossa contains the opening of the maxillary sinus, known as the ostium, which allows air to flow in and out of the sinus.

Clinical Significance

The clinical significance of the pterygopalatine fossa lies in the various structures and pathways that pass through it. Dysfunction or damage to any of these structures can lead to a range of clinical issues.

One potential issue is a blockage of the maxillary artery, which can lead to decreased blood flow to the head and neck region. This can cause symptoms such as headache, facial pain, and visual disturbances. In severe cases, it can also lead to tissue death (necrosis) due to lack of oxygen and nutrients.

Another potential issue is damage to the pterygopalatine ganglion, which can lead to problems with secretions and blood flow in the head and neck region. This can cause symptoms such as dry mouth, dry eyes, and decreased sweating. It can also lead to problems with digestion and absorption of nutrients due to impaired secretions in the digestive system.

Damage to the pterygoid canal or the pterygoid venous plexus can also lead to problems with blood drainage from the head and neck region. This can cause symptoms such as swelling, edema, and increased risk of bleeding or bruising.

In addition to these potential issues, the pterygopalatine fossa is also a common site for the development of certain types of tumors and other abnormalities. For example, neurogenic tumors, such as neurofibromas and schwannomas, can arise from the pterygopalatine ganglion. Tumors of the blood vessels, such as hemangiomas and lymphangiomas, can also occur in the pterygopalatine fossa. These types of tumors and abnormalities can cause a range of symptoms depending on their size and location, and they may require surgical removal or other types of treatment.

In this Article: