Advanced Bone Marrow Quiz
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This quiz contains 10 questions. Click below to begin.
Q1. Which specialized cells in the bone marrow support hematopoietic stem cells by secreting growth factors?
- Osteoclasts
- Stromal cells
- Chondrocytes
- Neutrophils
Q2. In which zone of the bone marrow are newly formed blood cells released into circulation?
- Subendothelial spaces
- Trabeculae
- Sinusoids
- Central veins
Q3. Which transcription factor is critical for self-renewal of hematopoietic stem cells?
- RUNX1
- MYC
- PAX5
- NF-κB
Q4. What is the primary energy source for quiescent hematopoietic stem cells?
- Anaerobic glycolysis
- Beta-oxidation
- Oxidative phosphorylation
- Gluconeogenesis
Q5. Which molecule anchors hematopoietic stem cells to the bone marrow niche?
- VEGF
- TNF-α
- CXCL12
- IL-7
Q6. Which type of bone marrow cell gives rise to osteoblasts?
- Monocytes
- Hematopoietic stem cells
- Mesenchymal stem cells
- Erythrocytes
Q7. Aplastic anemia is caused by failure of which bone marrow component?
- Osteoclasts
- Hematopoietic stem cells
- Mesenchymal stem cells
- Neurons
Q8. Which term describes the migration of hematopoietic stem cells from bone marrow into peripheral blood?
- Mobilization
- Extravasation
- Diapedesis
- Chemotaxis
Q9. Which cytokine is crucial for early lymphoid lineage commitment in the bone marrow?
- IL-7
- IL-3
- GM-CSF
- IL-6
Q10. Which condition involves replacement of normal marrow with fibrous tissue?
- Leukemia
- Myelofibrosis
- Aplastic anemia
- Polycythemia vera
