Advanced Bone Marrow Quiz
Ready to start the quiz?
This quiz contains 10 questions. Click below to begin.
Q1. Which specialized cells in the bone marrow support hematopoietic stem cells by secreting growth factors?
- Neutrophils
- Osteoclasts
- Chondrocytes
- Stromal cells
Q2. In which zone of the bone marrow are newly formed blood cells released into circulation?
- Central veins
- Sinusoids
- Trabeculae
- Subendothelial spaces
Q3. Which transcription factor is critical for self-renewal of hematopoietic stem cells?
- MYC
- PAX5
- NF-κB
- RUNX1
Q4. What is the primary energy source for quiescent hematopoietic stem cells?
- Oxidative phosphorylation
- Beta-oxidation
- Gluconeogenesis
- Anaerobic glycolysis
Q5. Which molecule anchors hematopoietic stem cells to the bone marrow niche?
- VEGF
- TNF-α
- CXCL12
- IL-7
Q6. Which type of bone marrow cell gives rise to osteoblasts?
- Hematopoietic stem cells
- Monocytes
- Mesenchymal stem cells
- Erythrocytes
Q7. Aplastic anemia is caused by failure of which bone marrow component?
- Hematopoietic stem cells
- Mesenchymal stem cells
- Neurons
- Osteoclasts
Q8. Which term describes the migration of hematopoietic stem cells from bone marrow into peripheral blood?
- Extravasation
- Mobilization
- Chemotaxis
- Diapedesis
Q9. Which cytokine is crucial for early lymphoid lineage commitment in the bone marrow?
- IL-7
- IL-6
- GM-CSF
- IL-3
Q10. Which condition involves replacement of normal marrow with fibrous tissue?
- Myelofibrosis
- Aplastic anemia
- Polycythemia vera
- Leukemia