Intermediate MALT Quiz

Q1. Which specialized epithelial cells transport luminal antigens toward immune cells in Peyer's patches?

• Parietal cells
• Paneth cells only
• Podocytes
• M cells

Q2. What is follicle-associated epithelium?

• The covering of articular cartilage
• The capsule of the spleen
• Specialized epithelium overlying organized mucosal lymphoid follicles
• The lining of a lymph node medullary sinus

Q3. Where are many diffuse immune cells of intestinal MALT located?

• Serosa only
• Lamina propria
• Periosteum
• Muscularis externa only

Q4. What distinguishes Peyer's patches from isolated lymphoid follicles?

• Peyer's patches contain no lymphocytes
• Isolated follicles occur only in the thymus
• Peyer's patches contain aggregated lymphoid follicles
• Peyer's patches are venous structures

Q5. In which part of the small intestine are Peyer's patches typically most developed?

• Ileum
• Gastric antrum
• Proximal jejunum only
• Duodenum

Q6. How does appendiceal lymphoid tissue differ structurally from a typical lymph node?

• It is a primary organ for T cell maturation
• It contains no lymphoid follicles
• It filters circulating blood through red pulp
• It is integrated into the intestinal wall rather than forming a typical encapsulated node

Q7. What does BALT refer to?

• Bone-associated lymphatic tissue
• Biliary arterial lymphatic tissue
• Brain-associated lymphoid tissue
• Bronchus-associated lymphoid tissue

Q8. What occurs in germinal centers of activated MALT follicles?

• Erythrocyte destruction
• Activated B cell proliferation and selection
• T cell maturation from hematopoietic precursors
• Smooth muscle regeneration

Q9. Why are plasma cells common in the mucosal lamina propria?

• They form the epithelial basement membrane
• They produce antibodies that contribute to mucosal defense
• They generate intestinal smooth muscle
• They create lymphatic valves

Q10. How can material from the intestinal lumen reach immune cells associated with Peyer's patches?

• M cells transport sampled material across follicle-associated epithelium
• It crosses periosteum into bone
• It must first pass through the renal glomerulus
• It travels through the thymic capsule