Intermediate Nephron Quiz

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This quiz contains 10 questions. Click below to begin.

Q1. What pressure drives filtration at the glomerulus?

  • Renal arterial pressure
  • Colloid osmotic pressure
  • Bowman’s capsule pressure
  • Glomerular hydrostatic pressure

Q2. Which layer of the filtration barrier prevents passage of large plasma proteins?

  • Visceral epithelium
  • Basement membrane
  • Fenestrated endothelium
  • Parietal layer of Bowman’s capsule

Q3. What is the role of podocytes in the glomerulus?

  • Absorb glucose from filtrate
  • Store calcium
  • Create filtration slits
  • Produce erythropoietin

Q4. Which region of the nephron has the highest water permeability?

  • Distal tubule
  • Descending limb of loop of Henle
  • Proximal tubule
  • Thick ascending limb

Q5. What substance is secreted by the proximal tubule to help eliminate drugs?

  • Aldosterone
  • Para-aminohippurate (PAH)
  • Creatinine
  • Antidiuretic hormone

Q6. Which ion is actively reabsorbed in the thick ascending limb of the loop of Henle?

  • HCO₃⁻ only
  • Na⁺, K⁺, and Cl⁻
  • Ca²⁺ only
  • Phosphate

Q7. How does aldosterone affect the nephron?

  • Blocks bicarbonate secretion
  • Increases Na⁺ reabsorption, K⁺ secretion
  • Inhibits water reabsorption
  • Decreases Na⁺ reabsorption, retains K⁺

Q8. Where is the juxtaglomerular apparatus located?

  • Near vascular pole of glomerulus
  • At renal pelvis junction
  • Inside the loop of Henle
  • In adrenal cortex

Q9. What is the function of macula densa cells?

  • Secrete ADH
  • Monitor NaCl and regulate GFR
  • Filter urea
  • Reabsorb glucose

Q10. Which portion of the nephron is impermeable to water but reabsorbs ions?

  • Bowman’s capsule
  • Collecting duct
  • Thick ascending limb of loop of Henle
  • Descending limb of loop of Henle
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