Advanced Thyroid Quiz

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This quiz contains 10 questions. Click below to begin.

Q1. Which transcription factor is critical for thyroid follicular cell development?

  • TTF-1
  • Nkx2.5
  • HoxA3
  • PAX8

Q2. How does thyroid hormone exert its effects at the cellular level?

  • By binding nuclear receptors
  • By degrading mRNA
  • By altering membrane channels
  • By binding cell surface receptors

Q3. Where is thyroglobulin synthesized and stored?

  • In the Golgi apparatus
  • In cytoplasm
  • In the colloid
  • Inside mitochondria

Q4. What enzyme is responsible for iodine organification in the thyroid?

  • Thyroid peroxidase (TPO)
  • Aromatase
  • Deiodinase
  • 5-alpha reductase

Q5. Which pathway controls TSH secretion from the anterior pituitary?

  • JAK-STAT pathway
  • HPA axis
  • HPT axis
  • RAS pathway

Q6. Why does Graves’ disease cause hyperthyroidism?

  • Iodine deficiency
  • TSH deficiency
  • Destruction of thyroid tissue
  • Autoantibodies stimulate TSH receptors

Q7. Which nerve is most at risk during thyroid surgery?

  • Accessory nerve
  • Vagus nerve
  • Phrenic nerve
  • Recurrent laryngeal nerve

Q8. What is the most common type of thyroid cancer?

  • Papillary thyroid carcinoma
  • Follicular carcinoma
  • Medullary carcinoma
  • Anaplastic carcinoma

Q9. Which radioactive isotope is commonly used in thyroid scans?

  • Gallium-67
  • Technetium-99m
  • Iodine-131
  • Iodine-123

Q10. How does thyroid hormone influence fetal development?

  • Important only for bone formation
  • Only needed after birth
  • Important for muscle development
  • Crucial for brain and skeletal development
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