Advanced Thyroid Quiz

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This quiz contains 10 questions. Click below to begin.

Q1. Which transcription factor is critical for thyroid follicular cell development?

  • TTF-1
  • PAX8
  • HoxA3
  • Nkx2.5

Q2. How does thyroid hormone exert its effects at the cellular level?

  • By degrading mRNA
  • By altering membrane channels
  • By binding cell surface receptors
  • By binding nuclear receptors

Q3. Where is thyroglobulin synthesized and stored?

  • Inside mitochondria
  • In the colloid
  • In the Golgi apparatus
  • In cytoplasm

Q4. What enzyme is responsible for iodine organification in the thyroid?

  • 5-alpha reductase
  • Thyroid peroxidase (TPO)
  • Deiodinase
  • Aromatase

Q5. Which pathway controls TSH secretion from the anterior pituitary?

  • HPT axis
  • JAK-STAT pathway
  • HPA axis
  • RAS pathway

Q6. Why does Graves’ disease cause hyperthyroidism?

  • TSH deficiency
  • Destruction of thyroid tissue
  • Autoantibodies stimulate TSH receptors
  • Iodine deficiency

Q7. Which nerve is most at risk during thyroid surgery?

  • Phrenic nerve
  • Accessory nerve
  • Recurrent laryngeal nerve
  • Vagus nerve

Q8. What is the most common type of thyroid cancer?

  • Medullary carcinoma
  • Papillary thyroid carcinoma
  • Follicular carcinoma
  • Anaplastic carcinoma

Q9. Which radioactive isotope is commonly used in thyroid scans?

  • Gallium-67
  • Iodine-131
  • Iodine-123
  • Technetium-99m

Q10. How does thyroid hormone influence fetal development?

  • Important only for bone formation
  • Important for muscle development
  • Only needed after birth
  • Crucial for brain and skeletal development