Intermediate Zona Fasciculata Quiz

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This quiz contains 10 questions. Click below to begin.

Q1. What separates the cords of zona fasciculata cells?

  • Collecting ducts
  • Cartilage plates
  • Lymphoid follicles
  • Sinusoidal capillaries

Q2. Which organelle is especially abundant in zona fasciculata cells because of their steroidogenic function?

  • Cilia
  • Myofibrils
  • Rough endoplasmic reticulum only
  • Smooth endoplasmic reticulum

Q3. What mitochondrial feature is characteristic of steroid-producing zona fasciculata cells?

  • No cristae
  • Internal cartilage septa
  • Only flat lamellar cristae typical of many nonsteroidogenic cells
  • Tubular or vesicular cristae

Q4. What is stored in the abundant cytoplasmic droplets of zona fasciculata cells?

  • Bile pigments
  • Glycosaminoglycans only
  • Catecholamines
  • Cholesterol and cholesterol esters

Q5. Which hypothalamic-pituitary pathway regulates zona fasciculata cortisol production?

  • ADH-oxytocin axis
  • GnRH-LH axis only
  • CRH-ACTH axis
  • TRH-TSH axis

Q6. Which receptor mediates the principal action of ACTH on zona fasciculata cells?

  • Melanocortin 2 receptor
  • Insulin receptor
  • Nicotinic acetylcholine receptor
  • Beta-1 adrenergic receptor

Q7. Which intracellular signaling pathway is activated prominently by ACTH in zona fasciculata cells?

  • Nuclear thyroid receptor signaling
  • IP3 pathway exclusively through muscarinic receptors
  • Voltage-gated sodium channels only
  • cAMP and protein kinase A pathway

Q8. What is the direction of blood flow through cortical sinusoids associated with the zona fasciculata?

  • From the central vein directly to the capsule
  • From the renal pelvis into the cortex
  • From the medulla outward only
  • From the outer cortex inward toward the medulla

Q9. How does ACTH support the structure of the zona fasciculata in addition to stimulating secretion?

  • It removes all intracellular lipid
  • It blocks cortical blood flow
  • It converts fasciculata cells into chromaffin cells
  • It provides trophic support to cortical cells

Q10. Which adrenal cortical zone lies immediately deep to the zona fasciculata?

  • Zona glomerulosa
  • Zona reticularis
  • Renal cortex
  • Adrenal capsule
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