Intermediate Zona Glomerulosa Quiz
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This quiz contains 10 questions. Click below to begin.
Q1. Which enzyme is characteristic of terminal aldosterone synthesis in zona glomerulosa cells?
- Tyrosine hydroxylase
- Aldosterone synthase
- PNMT
- Renin
Q2. Which steroidogenic enzyme activity is notably absent or very low in zona glomerulosa cells?
- 3-beta-hydroxysteroid dehydrogenase
- 17-alpha-hydroxylase
- Cholesterol side-chain cleavage enzyme
- Aldosterone synthase
Q3. Which angiotensin peptide directly stimulates zona glomerulosa cells to secrete aldosterone?
- Angiotensinogen
- Bradykinin
- Angiotensin I only
- Angiotensin II
Q4. Which receptor mediates the major direct action of angiotensin II on zona glomerulosa cells?
- AT1 receptor
- Nicotinic acetylcholine receptor
- Melanocortin 2 receptor exclusively
- Beta-1 adrenergic receptor
Q5. How does elevated extracellular potassium stimulate zona glomerulosa cells?
- Membrane depolarization and increased intracellular calcium
- Activation of skeletal muscle contraction
- Inhibition of all calcium entry
- Complete membrane hyperpolarization
Q6. What type of capillaries are associated with zona glomerulosa and the rest of the adrenal cortex?
- Avascular connective tissue channels
- Lymphatic vessels only
- Fenestrated sinusoidal capillaries
- Blood-brain barrier capillaries
Q7. From where does blood enter the superficial adrenal cortex near the zona glomerulosa?
- Subcapsular arterial plexus
- Portal venous sinus
- Renal pelvis
- Central adrenal vein
Q8. What is the general direction of blood flow from the zona glomerulosa through the adrenal cortex?
- Outward from the medulla only
- Inward toward deeper cortex and medulla
- Directly into the peritoneal cavity
- Into the renal collecting system
Q9. How does ACTH compare with angiotensin II as a regulator of zona glomerulosa function?
- ACTH is the only regulator of aldosterone
- Zona glomerulosa has no hormonal regulation
- ACTH has a secondary role compared with angiotensin II and potassium
- ACTH completely suppresses aldosterone
Q10. Which intracellular organelles are prominent in zona glomerulosa cells because they synthesize steroids?
- Large mucin granules only
- Smooth endoplasmic reticulum and steroidogenic mitochondria
- Keratin bundles and cartilage
- Cilia and myofibrils