External iliac vein

Medically Reviewed by Anatomy Team

The external iliac vein is a large, deep vein located in the pelvic region. It is formed by the confluence of the femoral vein and the deep circumflex iliac vein near the inguinal ligament. It runs superiorly along the pelvic brim, following the course of the external iliac artery. The external iliac vein passes beneath the inguinal ligament as it ascends into the pelvic region, where it merges with the internal iliac vein to form the common iliac vein. The external iliac vein is responsible for draining blood from the lower limbs and parts of the lower abdominal wall and pelvis.

Location and Structure

The external iliac vein is a large, deep vein located in the lower pelvis, running along the pelvic brim. It forms part of the major venous drainage system of the lower limbs and pelvis. The vein is paired, with one on each side of the body, and it is situated alongside the external iliac artery, which follows a similar course. The external iliac vein lies medial to the external iliac artery and is larger in diameter than the artery due to the greater volume of blood it carries back toward the heart.

Anatomy

Origin and Course

The external iliac vein is formed at the inguinal ligament from the confluence of the femoral vein and the deep circumflex iliac vein. It continues its upward course along the pelvic brim, traveling medially and slightly posteriorly in relation to the external iliac artery. The vein follows the curvature of the pelvis, moving superiorly toward the lumbar region.

As the external iliac vein ascends, it passes through the pelvic region until it reaches the sacroiliac joint, where it merges with the internal iliac vein. This confluence of the external and internal iliac veins forms the common iliac vein, which continues its course toward the inferior vena cava. The external iliac vein is responsible for transporting blood from the lower extremities and portions of the pelvis and abdominal wall into the larger venous system.

Confluence with the Internal Iliac Vein

The external iliac vein joins with the internal iliac vein at the level of the sacroiliac joint to form the common iliac vein. The internal iliac vein drains blood from the pelvic organs, including the bladder, rectum, and reproductive organs, while the external iliac vein primarily drains blood from the lower extremities. The point where the two veins merge forms an important junction in the venous system, marking the transition of blood from the legs and pelvis into the larger inferior vena cava, which ultimately carries blood to the heart.

Tributaries

The external iliac vein receives several important tributaries as it ascends through the pelvic region. These tributaries help drain blood from the lower limbs, pelvis, and lower abdominal wall. The main tributaries include:

  • Femoral vein: The primary deep vein of the lower limb, the femoral vein carries blood from the thigh, leg, and foot and drains directly into the external iliac vein.
  • Deep circumflex iliac vein: This vein drains blood from the lower abdominal wall and the iliac crest. It merges with the femoral vein before both converge to form the external iliac vein.
  • Inferior epigastric vein: This vein drains the lower anterior abdominal wall and ascends to join the external iliac vein near the inguinal ligament.

These tributaries play a crucial role in ensuring the proper drainage of blood from the lower body, ultimately contributing to the return of deoxygenated blood to the heart.

Relationship with Surrounding Structures

The external iliac vein is closely associated with several important anatomical structures. It runs medially and posteriorly to the external iliac artery, which follows a nearly parallel course. The vein and artery are enclosed within the iliac sheath, a layer of connective tissue that supports these vessels as they travel through the pelvis.

The external iliac vein is also situated near several structures of the pelvic cavity, including the inguinal ligament, which marks its origin, and the psoas major muscle, which lies posterior to the vein. As the vein ascends, it passes close to the obturator nerve, which runs along its lateral side. The proximity of the vein to these structures is an important consideration during surgical procedures in the pelvic region.

Valves

The external iliac vein contains one-way valves that help maintain the direction of blood flow toward the heart. These valves prevent the backflow of blood, particularly when a person is standing or sitting, and ensure that venous return from the lower limbs occurs efficiently. The number and distribution of valves in the external iliac vein can vary, but they play a key role in maintaining proper circulation, especially under the influence of gravity.

Variations in Anatomy

The anatomy of the external iliac vein can exhibit some variations between individuals. In some cases, the size and course of the vein may differ, and the number of tributaries may vary. For instance, the deep circumflex iliac vein or inferior epigastric vein may have additional branches that merge with the external iliac vein at different points along its course. These anatomical variations are important during surgical procedures, as they can influence the approach to accessing the vein or addressing venous conditions. Additionally, rare anatomical anomalies, such as duplicated external iliac veins, have been reported, although these are uncommon.

Function

Venous Drainage of the Lower Limbs

The primary function of the external iliac vein is to drain deoxygenated blood from the lower limbs. It receives blood from the femoral vein, which collects venous blood from the foot, leg, and thigh, and transports it upward toward the pelvis. The femoral vein, being the major deep vein of the leg, plays a critical role in returning blood from the lower extremities to the heart, and the external iliac vein acts as a crucial pathway in this process. Once the femoral vein merges with the deep circumflex iliac vein, it becomes the external iliac vein, which continues the transport of venous blood back toward the heart.

Venous Drainage of the Lower Abdominal Wall and Pelvis

The external iliac vein also functions to drain blood from the lower abdominal wall and portions of the pelvis. It receives blood from the inferior epigastric vein, which drains the lower anterior abdominal wall, and the deep circumflex iliac vein, which drains the iliac crest and surrounding tissues. This ensures that venous blood from the lower abdomen and pelvic areas is efficiently collected and transported into the deeper venous system, maintaining proper circulation in these regions.

Connection with the Internal Iliac Vein

The external iliac vein plays a critical role in integrating blood flow from the lower limbs and pelvis. As it ascends through the pelvic region, it joins with the internal iliac vein at the sacroiliac joint to form the common iliac vein. The internal iliac vein drains blood from the pelvic organs, including the bladder, reproductive organs, and rectum. By combining with the internal iliac vein, the external iliac vein ensures that venous blood from both the lower extremities and the pelvic organs is channeled into the common iliac vein, where it can then continue toward the inferior vena cava and ultimately to the heart. This connection allows for the efficient transport of blood from the entire lower body.

Prevention of Venous Reflux

The external iliac vein is equipped with one-way valves, which are essential for preventing venous reflux—the backward flow of blood. These valves ensure that blood flows in one direction, from the lower limbs and pelvis toward the heart. This function is especially important when the body is in an upright position, as gravity can exert pressure on the venous system. The valves within the external iliac vein close to prevent blood from pooling or flowing back into the legs and pelvis, maintaining proper venous return and preventing conditions like venous insufficiency or varicose veins in the lower extremities.

Role in the Venous Return System

The external iliac vein plays a central role in the overall venous return system by acting as the primary conduit for blood returning from the lower body to the heart. It facilitates the transport of venous blood from the lower limbs and pelvis into the common iliac vein, which subsequently drains into the inferior vena cava. The efficient return of deoxygenated blood to the heart is essential for maintaining the circulatory system, allowing the blood to be re-oxygenated in the lungs and recirculated throughout the body. The external iliac vein, therefore, plays a vital role in sustaining the body’s cardiovascular function.

Venous Return During Physical Activity

During physical activity, the external iliac vein is involved in supporting the increased demand for venous return from the lower limbs. When walking, running, or performing other physical activities, the muscles of the legs and pelvis contract, compressing the veins and pushing blood upward. This process, known as the muscle pump mechanism, helps move blood against the force of gravity. The external iliac vein, being one of the larger veins in the pelvis, plays a crucial role in ensuring that this increased blood flow from the lower body is efficiently channeled toward the heart during physical exertion.

Removal of Metabolic Waste

The external iliac vein is responsible for removing metabolic waste products from the tissues of the lower limbs, pelvis, and lower abdomen. As it drains deoxygenated blood, it carries waste materials such as carbon dioxide, lactate, and other byproducts of cellular metabolism away from these regions. This waste-laden blood is then transported to the heart and lungs, where it can be oxygenated and the waste products can be eliminated from the body. The efficient removal of metabolic byproducts is essential for maintaining tissue health and preventing the accumulation of toxins in the lower body.

Integration with the Pelvic Circulatory System

The external iliac vein forms a critical link in the broader pelvic circulatory system. By receiving blood from smaller tributaries such as the inferior epigastric vein and the deep circumflex iliac vein, the external iliac vein ensures that blood from the pelvic region and lower abdominal wall is properly integrated into the systemic venous circulation. This connection is vital for maintaining balanced blood flow from the entire pelvic region, ensuring that both the deep and superficial venous systems work together to return blood to the heart.

Contribution to Pressure Regulation

The external iliac vein plays a role in regulating venous pressure within the lower limbs and pelvis. During periods of increased intra-abdominal pressure, such as during coughing, heavy lifting, or straining, the external iliac vein helps to manage venous return by accommodating increased blood flow from the lower body. This regulation of venous pressure is essential for preventing venous congestion or pooling, which could lead to discomfort or swelling in the legs or pelvic region. The ability of the external iliac vein to adapt to changes in pressure helps maintain proper circulation, especially during activities that place stress on the venous system.

Clinical Significance

The external iliac vein is clinically significant due to its role in various conditions affecting the venous system of the lower limbs and pelvis. It is a critical structure in deep vein thrombosis (DVT), where blood clots can form in the vein, potentially leading to serious complications like pulmonary embolism if the clot dislodges and travels to the lungs. The vein is also important during pelvic and vascular surgeries, such as hip replacements or repairs of aneurysms, where accidental injury to the vein can lead to significant bleeding or other complications. Additionally, the external iliac vein is frequently used in venous catheterization for procedures like dialysis access or central venous monitoring. Its location and size make it an important vessel in clinical diagnostics and treatment, often evaluated using imaging techniques like ultrasound or CT angiography to assess for blockages or abnormalities.

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