Greater palatine nerve

Medically Reviewed by Anatomy Team

The greater palatine nerve is a branch of the maxillary nerve, which is a division of the trigeminal nerve (CN V). The trigeminal nerve is the largest of the cranial nerves and is responsible for sensation in the face and mouth, as well as for the muscles of mastication (chewing).

Structure

The greater palatine nerve is a mixed nerve, meaning that it carries both sensory and motor fibers. It arises from the pterygopalatine ganglion, a collection of nerve cell bodies located within the pterygopalatine fossa, a small cavity in the skull. From here, the nerve travels through the pterygomaxillary fissure, a small opening in the skull, and into the oral cavity.

Within the oral cavity, the greater palatine nerve divides into several branches. The largest branch, the greater palatine artery, supplies blood to the hard and soft palate, as well as to the gums and teeth. The other branches of the greater palatine nerve include the lesser palatine nerves, which innervate the soft palate, and the nasopalatine nerves, which innervate the nasal septum and the front part of the hard palate.

Location

The greater palatine nerve is located within the oral cavity, specifically in the hard and soft palate. The hard palate is the bony portion of the roof of the mouth, while the soft palate is the muscular portion that separates the oral cavity from the nasal cavity.

Function

The greater palatine nerve has both sensory and motor functions. Sensory fibers of the greater palatine nerve carry sensory information from the hard and soft palate to the brain, allowing us to perceive touch, temperature, and pain in these areas. Motor fibers of the greater palatine nerve innervate the muscles of the soft palate, allowing us to move the soft palate during swallowing and speech.

Clinical significance

Damage to the greater palatine nerve can result in sensory deficits in the hard and soft palate, as well as weakness in the muscles of the soft palate. This can lead to difficulties with swallowing and speaking.

In addition, the greater palatine nerve can be affected by certain medical conditions. For example, it can be damaged during surgery to remove tumors in the oral cavity, or it can be compressed by a cyst or abscess in the pterygopalatine fossa.

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