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Nasopharynx

Medically Reviewed by Anatomy Team

Table of Contents

The nasopharynx is the uppermost part of the pharynx, situated posterior to the nasal cavity and above the soft palate.[7] It serves as a passageway for air from the nasal cavity to the oropharynx and plays a critical role in respiration and immune defense. The nasopharynx is lined by a ciliated pseudostratified columnar epithelium, facilitating mucociliary clearance.

Anatomy and Boundaries

Superior Boundary (Roof):

Formed by the sphenoid bone and basilar part of the occipital bone.

Inferior Boundary (Floor):

Continuous with the oropharynx below the soft palate.[5]

Anterior Boundary:

Opens into the nasal cavity through the choanae.[8]

Posterior Boundary:

Lies against the prevertebral fascia and muscles.

Lateral Boundaries:

  • Houses the pharyngeal opening of the Eustachian tube, which connects to the middle ear.
  • Contains the tubal tonsils and pharyngeal recess (fossa of Rosenmüller).

Structural Features

  • Epithelial Lining: Lined by pseudostratified ciliated columnar epithelium with goblet cells that produce mucus for trapping particles and pathogens.[1]
  • Adenoid (Pharyngeal Tonsils): Located in the roof and posterior wall of the nasopharynx, part of the immune system’s first line of defense.
  • Eustachian Tube Openings: Maintain pressure equilibrium between the nasopharynx and middle ear.
  • Muscular Layer: Consists of the superior constrictor muscle, which helps in swallowing.

Function

  • Air Conduction: Acts as a conduit for airflow between the nasal cavity and the lower respiratory tract.
  • Protection and Immunity: Contains lymphoid tissue (adenoids) to trap and neutralize pathogens.[4]
  • Pressure Regulation: The Eustachian tube openings equalize air pressure in the middle ear.
  • Mucociliary Clearance: Cilia transport mucus and trapped particles toward the oropharynx for clearance.[3]
  • Speech and Resonance: Acts as a resonating chamber, contributing to vocal quality.

Clinical Significance

Adenoid Hypertrophy

Enlargement of the adenoids can cause nasal obstruction, snoring, and recurrent ear infections.

Nasopharyngitis

Inflammation caused by viral or bacterial infections, often resulting in sore throat and nasal congestion.

Otitis Media

Dysfunction of the Eustachian tube can lead to fluid buildup and infection in the middle ear.

Nasopharyngeal Carcinoma

A rare but serious cancer arising in the epithelial lining, often associated with Epstein-Barr virus (EBV).

Sleep Apnea

Blockage of airflow due to enlarged adenoids or soft tissue collapse can lead to obstructive sleep apnea.

Foreign Bodies and Trauma

The nasopharynx can be affected by accidental insertion of foreign objects, especially in children.

The nasopharynx is an anatomically and functionally significant region of the upper airway that facilitates breathing, immunity, and pressure regulation.[6] Its close relationship with adjacent structures like the Eustachian tube and adenoids makes it clinically relevant in respiratory and ENT (ear, nose, and throat) disorders.[2] Understanding its anatomy and functions is crucial for diagnosing and managing related conditions effectively.

References

  1. Moore KL, Dalley AF, Agur AMR. Clinically Oriented Anatomy. 8th ed. Wolters Kluwer; 2017. ISBN 978-1496347213.
  2. Standring S. Gray’s Anatomy: The Anatomical Basis of Clinical Practice. 41st ed. Elsevier; 2016. ISBN 978-0702052309.
  3. Netter FH. Atlas of Human Anatomy. 8th ed. Elsevier; 2022. ISBN 978-0323680424.
  4. Maran AGD, Lund VJ. Clinical Anatomy of the Nose and Paranasal Sinuses. Churchill Livingstone; 1990. ISBN 978-0443042129.
  5. Sinnatamby CS. Last’s Anatomy: Regional and Applied. 13th ed. Elsevier; 2018. ISBN 978-0702073250.
  6. Drake RL, Vogl AW, Mitchell AWM. Gray’s Anatomy for Students. 4th ed. Elsevier; 2020. ISBN 978-0323393041.
  7. Goss CM. Gray’s Anatomy of the Human Body. 29th ed. Lea & Febiger; 1973. ISBN 978-0812106442.
  8. Kamel KS, Reddy R. Applied Head and Neck Anatomy for the Facial Cosmetic Surgeon. 1st ed. Springer; 2014. ISBN 978-3642546005.