Radial nerve

Medically Reviewed by Anatomy Team

The radial nerve is one of the major peripheral nerves of the upper limb and is crucial for both sensory and motor functions. It originates from the posterior cord of the brachial plexus and primarily innervates the extensor muscles of the forearm.

Structure

  • Type: The radial nerve is a mixed nerve, consisting of both motor and sensory fibers.
  • Origin: It originates from the posterior cord of the brachial plexus, generally deriving fibers from the C5 to T1 nerve roots.
  • Branches: The nerve gives off several branches along its course, including branches to the triceps, the cutaneous branches to provide sensation to the arm, and the deep branch (which later becomes the posterior interosseous nerve) that supplies the extensor muscles of the forearm.

Location

  • Origin and Course: The radial nerve originates in the axillary region, close to the axillary artery. It wraps around the humerus, running in the spiral (or radial) groove along with the deep brachial artery.
  • Pathway: After spiraling around the humerus, the nerve enters the forearm where it divides into superficial and deep branches. The superficial branch is primarily sensory and runs under the brachioradialis muscle to innervate the dorsum of the hand. The deep branch is mainly motor and goes on to become the posterior interosseous nerve, supplying the extensor muscles of the forearm.
  • Innervation Points:
    • Motor: Supplies the triceps brachii, anconeus, and the extensor muscles in the posterior compartment of the forearm.
    • Sensory: Provides sensation to the posterior surface of the arm and forearm as well as the dorsum of the hand, particularly the thumb, index, and middle fingers, and part of the ring finger.

Functions

The radial nerve has diverse functions due to its extensive sensory and motor innervation in the upper limb.

Here are its functions in detail:

Motor Functions

  • Arm Muscles: In the upper arm, the radial nerve supplies the triceps brachii, which is responsible for elbow extension, and the anconeus, which assists in this action. It also gives minor contributions to the brachialis and brachioradialis muscles, involved in elbow flexion.
  • Forearm Extensors: The deep branch of the radial nerve, which becomes the posterior interosseous nerve, innervates all the muscles in the posterior compartment of the forearm. These muscles are involved in wrist and finger extension, as well as forearm supination.
  • Supinator Muscle: The deep branch also supplies the supinator muscle, which plays a role in rotating the forearm into a supinated (or palm-up) position.

Sensory Functions

  • Cutaneous Sensation: The radial nerve provides sensory innervation to the skin over the posterior surface of the arm and forearm.
  • Dorsum of the Hand: The superficial branch of the radial nerve supplies sensation to the dorsal aspect of the hand, particularly over the proximal areas of the thumb, index, and middle fingers, as well as a portion of the ring finger.

Integrated Functions

  • Wrist and Finger Extension: By controlling the extensor muscles, the radial nerve plays a critical role in activities that require wrist and finger extension, such as opening a jar or pushing open a door.
  • Grip Strength: Though the radial nerve is primarily associated with extension, its function is essential for a strong grip. You need to extend your wrist to grip things properly, and dysfunction of the radial nerve can severely affect this ability.
  • Sensory Feedback: The sensory function of the radial nerve is vital for activities that require manipulation and positioning of the arm, forearm, and hand, providing essential feedback for both gross and fine motor tasks.

Clinical significance

The radial nerve is of significant clinical importance due to its extensive role in both motor and sensory functions of the arm and hand. Here’s a brief note on its clinical relevance:

Diagnostic Importance

  • Wrist Drop: One of the most characteristic signs of radial nerve injury is wrist drop, where the affected individual is unable to extend the wrist and fingers. This is often a diagnostic clue pointing to radial nerve dysfunction.
  • Sensory Deficits: Loss or alteration of sensation in the posterior aspect of the arm, forearm, and dorsum of the hand can indicate injury or dysfunction of the radial nerve or its branches.
  • Clinical Tests: Tests like the “finger drop test” or “wrist drop test” are used to assess the integrity of the radial nerve.

Clinical Conditions

  • Nerve Injury: The radial nerve can be injured due to fractures of the humerus, especially those involving the spiral groove, or during surgical procedures on the arm.
  • Compression Syndromes: The radial nerve can be compressed in conditions like “Saturday night palsy,” where prolonged pressure on the nerve leads to temporary dysfunction.
  • Peripheral Neuropathy: Conditions like diabetes can cause peripheral neuropathy affecting the radial nerve, resulting in both sensory and motor deficits.

Therapeutic Implications

  • Orthotic Devices: In cases of radial nerve injury leading to wrist drop, splints or other orthotic devices may be used to support the wrist in a functional position.
  • Rehabilitation: Physical therapy can be instrumental in recovering function after radial nerve injury, focusing on strengthening the extensor muscles and improving fine motor skills.
  • Surgical Repair: In severe cases involving nerve transection, surgical nerve repair or grafting may be necessary.

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